منابع مشابه
Leticia Arroyo Abad
Using a new dataset, this paper presents new evidence on inequality in Latin America for the 19th century and studies the effects of factor endowments and trade on inequality. Recent research has highlighted the link between the colonial origins of inequality and its persistence in Latin America. We find that inequality varied substantially throughout the century a...
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Özetçe. Yazılım geliştirme organizasyonları iş yapış yöntemlerini kontrol altına alarak daha kaliteli ürünler üreterek faaliyet alanlarında yaşamlarını sürdürebilmek amacı ile yazılım olgunluk modellerini kullanıma almaktadırlar. Yaygın olarak kullanılan CMMI ve ISO 15504 olgunluk modellerinde beş olgunluk seviyesi bulunmaktadır. 4. ve 5. seviyeler "Yüksek Olgunluk Seviyeleri" olarak adlandırıl...
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Mitochondrial dysfunction is a hallmark of beta-amyloid (Abeta)-induced neuronal toxicity in Alzheimer's disease (AD). Here, we demonstrate that Abeta-binding alcohol dehydrogenase (ABAD) is a direct molecular link from Abeta to mitochondrial toxicity. Abeta interacts with ABAD in the mitochondria of AD patients and transgenic mice. The crystal structure of Abeta-bound ABAD shows substantial de...
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Alzheimer's disease (AD) is a conformational disease that is characterized by amyloid-β (Aβ) deposition in the brain. Aβ exerts its toxicity in part by receptor-mediated interactions that cause down-stream protein misfolding and aggregation, as well as mitochondrial dysfunction. Recent reports indicate that Aβ may also interact directly with intracellular proteins such as the mitochondrial enzy...
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ژورنال
عنوان ژورنال: Ankara Üniversitesi İlahiyat Fakültesi Dergisi
سال: 1953
ISSN: 1301-0522
DOI: 10.1501/ilhfak_0000001136